Vyvanse is known to cause memory problems

Something is happening in the drug treatment of hyperkinetic syndrome (ADHD). Up to now it has been relatively uncommon in Germany to use amphetamines for drug treatment. No “finished product” from a pharmaceutical manufacturer was available for this purpose, rather a formulation of 0.2% DL-amphetamine sulfate juice had to be made by the pharmacist.

In the United States and Canada, amphetamines are more common than methylphenidate. Here especially “mixed salts” of amphetamines have become quite well known as Adderall®. Lisdexamfetamine (Vyvanse) is relatively new. The advantage of this drug, which only has the “clockwise” enantiomer dexamfetamine, is the long duration of action of 12-16 hours. In addition, the risk of abuse for non-ADHD users should be lower thanks to a pharmacological trick. An amino acid is chained to the active molecule and only separates from the active ingredient in the stomach. This makes the drug unsuitable for abuse through the nose or injections.

Now, with Attentin®, an amphetamine (dexamphetamine) has apparently been approved for the first time in Germany on December 1st, 2011, which is sold by the company Medice. As I understand it, with the restriction that initially (in addition to the mandatory non-drug treatment) attempts at therapy with methylphenidate AND atomoxetine (Strattera) did not have a good effect.

This is not entirely in line with international recommendations. There, methylphenidate and amphetamines are seen on an equal footing as “first line”, as the first-line drug, and then atomoxetine only with a small margin. If methylphenidate does not work (but the diagnosis is correct and a pharmacological response can actually be expected), one should first switch to amphetamines according to the American perspective. So: If you started with amphetamines such as Adderall or Vyvanse and did not have a good therapeutic effect, you should switch to methylphenidate.

I've used amphetamine juice quite often. In women with ADHD in particular, it appears a little “softer”, the “on-off effect” that occurs with MPH is not as strong. This means that with MPH in some patients a relatively sudden onset and a strong acute decrease in the effect can cause problems with the so-called rebound effect.
In addition, amphetamine can work better in stabilizing feelings in some patients. Here, however, caution is called for: You should / must not use amphetamine as a “euphorizer” and continue to dose it up until a “pink” mood is indicated. Some adult clients somehow bet they should be "fine" with the drug. One should only feel “more real”. And with ADHD, real means that you perceive the problems even more clearly so that you can then tackle them. But not that they are numbed or whitewashed.

You should therefore not use amphetamines if you have had previous drug experiences. Which should actually be clear. But then again and again we come across ADHD people who confuse fatigue with ADHD symptoms. And then practically tried amphetamines from illegality in order to “wake up”. So have been abused as an “upper”. The prescribing doctor has to be careful here. It goes without saying that the assassin will not be approved for adults or will be reimbursed by the insurance company for adults.